Top Ten Common Prejudices About Polyethylene Naphthalate Market.

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In 2014, the global polyethylene naphthalate market was worth USD 827.0 million, and it is expected to grow at a CAGR of 7.5 percent over the next five years. Because of its improved thermal and barrier properties, such as oxidation resistance, polyethylene naphthalate (PEN) is primarily used in packaging applications. Over the forecast period, rising demand for high-strength photographic films is likely to drive market expansion. polyethylene naphthalate market Because of their higher stiffness modulus, PEN films are a major component of food packaging applications, providing increased barrier properties and enhancing the material's strength. These films are also used to make pressure sensitive tapes and thermal sheets. They are also involved in the protection of solar cells. Forward integration of raw material providers in PEN manufacturing is a feature of the polyethylene naphthalate market. These businesses actively consume raw materials in order to create their products. Con...
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Ten Doubts You Should Clarify About Antisense Oligonucleotides Market.

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Antisense Oligonucleotides Market are single-stranded RNA or DNA molecules with a short length. Antisense oligonucleotides do not affect the activity of already generated proteins; rather, they act at the level of messenger RNA in the cell before proteins are made. Antisense oligonucleotides are employed in the therapy of cancer, CNS therapeutics, inflammatory therapeutics, diabetes, asthma, hair loss, and other diseases. In genomics, antisense oligonucleotides are also employed. Antisense nucleotides include fomivirsen, which is used to treat cytomegalovirus retinitis, and mipomersen, which is used to treat high cholesterol.


The rising number of launches pertaining to novel Antisense Oligonucleotides Market products by key players in the industry is one of the primary reasons driving growth of the global antisense oligonucleotides market. Exiqon A/S, which was bought by Qiagen in 2015, released novel LNA Antisense Oligonucleotide GapmeRs in 2015. In functional analysis, the LNA Antisense Oligonucleotide GapmeRs is employed to inactivate RNA. Existing siRNAs can be replaced with antisense LNA. LNA Antisense Oligonucleotide is created by combining an advanced bioinformatics technique with LNA (locked nucleic acid).


Furthermore, prominent companies' mergers and acquisitions to improve their product offerings are projected to be a major driver for the worldwide Antisense Oligonucleotides Market. For example, Takeda Pharmaceuticals Firm Ltd., a pharmaceutical company, combined with Wave Life Sciences Ltd., a nucleic acid therapeutics company, in February 2018. Takeda Pharmaceuticals and Wave Life Sciences Ltd. have joined to investigate antisense oligonucleotides for central nervous system disorders include Lou Gehrig's disease, Frontotemporal dementia (FTD), Spinocerebellar ataxia type 3 (SCA3), and Huntington's disease. Amyotrophic lateral sclerosis is another name for Lou Gehrig's disease.


Another aspect assisting the worldwide market's growth is a strong pipeline. Ionis Pharmaceuticals, for example, completed phase 2 clinical trials of their ISIS CRP Rx in 2016. In patients with paroxysmal atrial fibrillation, ISIS 329993 is an antisense oligonucleotide that targets CRP (C reactive protein). The Phase 2 clinical trials of Achieve Life Sciences' OGX 427 were completed in 2015. Castration-resistant prostate cancer is treated with OGX 427.


Over the projected period, North America is expected to be the leading region in the worldwide antisense oligonucleotides market. This is due to the region's rising approval of novel antisense oligonucleotide medications. For example, the United States Food and Drug Administration (FDA) authorised Nusinersen, a drug sold as Spinraza by Biogen Inc., a multinational biotechnology firm, in 2018. Nusinersen was the first medicine to be approved for the treatment of SMA (SMA). Furthermore, a strong pipeline is likely to contribute significantly to the growth of the antisense oligonucleotides market in North America.


In order to improve their product offers in antisense oligonucleotides, key firms in Europe are focusing on strategic mergers and acquisitions. This is also predicted to help the antisense oligonucleotides industry in Europe flourish. Astra Zeneca Plc, a multinational pharmaceutical and biopharmaceutical company, combined with Ionis Pharmaceuticals, a pharmaceutical firm, in 2014. Astra Zeneca Plc. has strategically merged with Ionis Pharmaceuticals to develop antisense oligonucleotide delivery technologies that will aid in more successfully targeting the intended tissue.


The merger also had the goal of developing Ligand Conjugation Antisense (LICA) Technology. Furthermore, a strong pipeline of important players is projected to help the market grow to some level. For example, in 2016, the pharmaceutical company Ionis Pharmaceuticals conducted a phase 2 clinical trial for its medication IONIS STAT 3Rx. Advanced malignancies and lymphoma are treated with IONIS STAT 3Rx.

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